There have been several revolutions in biotechnology that open the
door to many new products and technologies. The first, recombinant
DNA technology, allowed researchers for the first time to
“cut-and-splice” DNA in any way they wished, thereby making it
possible to assemble genes in new ways to manufacture a host of
proteins like insulin, growth hormone, and erythropoietin.
The
second revolution was called genomics and this technology allowed
researchers to rapidly sequence and manipulate gene sequence
information. Both recombinant DNA technology and genomics spawned
the development and growth of many of today’s leading biotechnology
companies.
In our opinion, regenerative medicine has the potential to be a
third major revolution in biotechnology. Empowered by the discovery
of human embryonic stem (ES) cells, regenerative medicine now has
the potential to produce any human cell type genetically modified in
any way, to be used in the treatment of a host of degenerative
diseases. Stem cells may also have commercial uses in the
development of experimental new drugs. Under the leadership of
Dr. Michael D. West, who pioneered this industry
after he founded Geron Corporation and later during his tenure at
Advanced Cell Technology, BioTime intends to become a significant
biotechnology company in this emerging sector, focusing on near-term
commercialization opportunities.